4F-MDMB-2201

Ucwaningo lwe-in vitro luphakamisa ukuthi i-compound ikhombisa ukuhlobana okuphezulu kwe-CB1 kanye ne-CB2 receptors futhi isebenze ekugxiliseni okuphansi. I-4F-MDMB-2201 iyi-homologue ye-5F-MDMB-2201. Ngaphezu kwalokho, ingumuthi osuselwe ku-indazole futhi ungowomndeni we-indazole-3-carboxamide. Ucwaningo olujwayelekile lomtholampilo lubonisa ukuthi i-4F-MDMB-2201 iyi-agonist enamandla futhi inobudlelwane obuphezulu be-CB1 receptor.

Igama le-IUPAC le-4F-MDMB-2201 lithi i-methyl2-(1-(4-cyanobutyl)-1h-indole-3-carboxamido)-3.3-dimethylbutanoate. Amanye amagama afanayo alo muthi wamakhemikhali yi-4F-MDMB-BICA, 4FBCA kanye ne-4FAKB. Ukusetshenziswa kwe-4F-MDMB kungabangela imiphumela emibi nemibi kubantu. Ngokwesisekelo semibiko yokuzenzela, kwacatshangwa ukuthi kubangela ukubona izinto ezingekho esibonwayo, ukudideka, ukudideka, ubuhlungu besifuba, ukuyaluza nokushaya kwenhliziyo okungajwayelekile. Ithengiswa ku-inthanethi njengomuthi womklami.

Lo mkhiqizo okwamanje awukho esitokisini futhi awutholakali.

Incazelo

Thenga i-4F-MDMB-2201 kusuka Ixoxo Lekhemikhali

I-4-fluoro-MDMB-2201 efushanisiwe njenge-4F-MDMB-2201 ithengiswa ku-inthanethi njengomuthi womklami. Inezici zama-cannabinoids endabuko okwenziwa. I-4F-MDMB-2201 i-homolog ye-5F-MDMB-2201. Ucwaningo lwe-in vitro luphakamisa ukuthi i-compound ikhombisa ukuhlobana okuphezulu kwama-receptors e-CB1 kanye ne-CB2 futhi iwavule ekugxilweni okuphansi. Ngaphezu kwalokho, ingumuthi osuselwe ku-indazole futhi ungowomndeni we-indazole-3-carboxamide.

Alukho ulwazi oluqondile olutholakalayo mayelana nezici zomtholampilo ze-4F-MDMB-2201. I-cannabis yaziwa nangokuthi imifino, i-ganja, utshani, kanye nokhula oluvame kakhulu. Ingaxutshwa nogwayi ukwenza i-spliff bese iyabhenywa. Ungathenga i-4F-MDMB-2201 ukuze uthole ucwaningo nezinye izinhlelo zokusebenza.

4F-MDMB-2201 VS 5F-MDMB-2201

Kokubili i-4F-MDMB-2201 kanye ne-5F-MDMB-2201 imithi emisha yabaklami kanye nezakhi zokwenziwa. Zinemiphumela enamandla engaba khona ohlelweni lwezinzwa olumaphakathi lwabantu. Imininingwane yamanje iphakamisa ukuthi zombili zithathwe esitshalweni samakhambi se-cannabinoid. Ku-5F-MDMB-2201 kukhona abangene esikhundleni ababili abakhona eringini endaweni engu-1 no-3. Isikhundla soku-1 sithathelwa indawo i-athomu ye-fluorine kuyilapho isikhundla sesi-3 sithathelwa indawo yiqembu le-amide.

Ngenxa yobukhona be-asymmetric carbon athomu, i-4F-MDMB-2201 ibonisa ukuthi ine-(R) kanye (S) -enantiomer. Kodwa i-4F-MDMB-2201 ivame ukutholakala njenge-(S) enantiomer.

Imininingwane ye-4F-MDMB-2201

Idatha ekhona iphakamisa ukuthi le nhlanganisela yamakhemikhali yabelana ngamagama ayo namanye ama-cannabinoids. Ucwaningo olujwayelekile lomtholampilo lubonisa ukuthi i-4F-MDMB-2201 iyi-agonist enamandla futhi inobudlelwane obuphezulu besamukeli se-CB1. Iza nefomula yamakhemikhali i-methyl2-(1-(4-cyanobutyl) -1h-indole-3-carboxamido) -3.3-dimethylbutanoate. Amanye amagama afanayo alo muthi wamakhemikhali yi-4F-MDMB-BICA, 4F-BCA kanye ne-4F-AKB.

Olunye ulwazi lobuchwepheshe luhlanganisa ifomula ye-Molecular: C20H28FN3O3 kanye ne-Formula Weight: 370 g/mol. Itholakala ngendlela eyimpuphu futhi inezimo ezifanele zokugcina; ingagcinwa iminyaka emibili. Thenga i-4F-MDMB-2201 powder ukuze ithengiswe kanye nezicelo zocwaningo.

Ingabe i-4F-MDMB-2201 Isemthethweni?

Ngokusho kwe-WHO kanye nebhodi lamazwe ngamazwe elilawula izidakamizwa, alukho ulwazi oluthile olutholakalayo mayelana nemizila kanye nokusetshenziswa okuphephile kwe-4F-MDMB-2201. Idatha yomtholampilo kanye nemibiko yokuzenzela akusekeli ukuba semthethweni kwalo muthi. Kuyisidakamizwa esisetshenziswa kabi futhi sifakwe ohlwini njengento yeshejuli II emazweni amaningi.

I-4F-MDMB-2201 iyisidakamizwa esivinjelwe ngenxa yemiphumela engaba khona ebanzi kubantu. Ucwaningo oluthile oluhlobene ne-toxicology yalo alukwazanga ukuhlonzwa okwamanje. Umsebenzisi kufanele aqaphele izakhi kanye nenani lento. Ikhiqizwa kuphela ngezinjongo zocwaningo abakhiqizi bamakhemikhali. Okunye ukusetshenziswa okusemthethweni nokungekho emthethweni kwalesi sidakamizwa akwaziwa okwamanje.

Ukusabela okubi kubantu

Ulwazi oluningiliziwe mayelana nokusetshenziswa kwe-4F-MDMB-2201 kubantu alutholakali. Idatha ehlanganisiwe evela emibikweni eyahlukene iphakamisa ukuthi ukusetshenziswa kwe-4F-MDMB kungabangela imiphumela emibi nemibi kubantu. Ngokwesisekelo sokuzibika, kwacatshangwa ukuthi kubangela ukubona izinto ezingekho, ukudideka, ukudideka, ubuhlungu besifuba, ukuyaluza, nokushaya kwenhliziyo okungajwayelekile.

Idatha eqoqwe ezimweni ezimbi kakhulu ihlanganisa imiphumela emibi kumasistimu wemizwa, amathumbu kanye nenhliziyo. Ukusetshenziswa okuvamile kuhlanganisa ukuzijabulisa, ukuphumula nokunciphisa ukukhathala kwemisipha. Akukho ukusetshenziswa okuqondile kwezentengiso nezimboni kwesigaba sezidakamizwa se-4F-MDMB-2201.

Amandla okuhlukumeza

Ukwakheka kanye nekhwalithi yale mithi ikhombisa ukuthi ihlobanisa izingozi zempilo yomphakathi nenhlalo. Imikhiqizo ijwayele ukusetshenziselwa izinjongo zokuzijabulisa ngabantu abacindezelekile ngokwengqondo nangokomzwelo. Ibhenywa ngokuyinhloko njengogwayi. I-4F-MDMDB iyisidakamizwa esihlukunyeziwe ngenxa yemiphumela yayo emibi ebulalayo futhi ayikho idatha ethembekile etholakalayo mayelana nomthamo. Abantu abazi ngemiphumela emibi engase ibe khona njengoba ithengiswa njengesidakamizwa sasekhaya.

Ayinconywa ukuthi isetshenziswe abantu kodwa iphakanyiswe kubantu ngabanye ukuthi ihlolwe izidakamizwa njengabashayeli neziboshwa. Ungayifaki impilo yakho engozini futhi uhlale uthintana nodokotela ukuze uthole imiphumela engcono.

Thenga i-4F-MDMB-2201

Ngocwaningo, izinhlelo zokusebenza zesayensi nokuhlolwa kwezidakamizwa kumasampula ebhayoloji, ungathenga i-4F-MDMB-2210 ithengiswa ku-inthanethi kanye nezicelo zocwaningo. Sihlinzeka ngezinhlobonhlobo zezidakamizwa namakhemikhali ocwaningo kumakhasimende ethu emhlabeni wonke. I-ChemicalFrog ibisebenzisana nemikhiqizo yocwaningo emsulwa iminyaka. Sesihambe ibanga elide ekuzuzeni ukwethenjwa amakhasimende ethu futhi sihlala sihlinzeka ngemithi esezingeni eliphezulu kakhulu.

Izidakamizwa zethu zilethwa emhlabeni wonke kososayensi, abacwaningi, abakhiqizi bamakhemikhali nabathengisi. Kukhona abathengisi abangathembekile emakethe futhi ukuthenga imikhiqizo yekhwalithi ephansi kusho ukuchitha isikhathi sakho nemali kokubili. Xhumana ne-ChemicalFrog ukuze uthole imiphumela engcono kakhulu yekhwalithi.

Kungani ukhethe i-Chemical Frog?

I-Chemical Frog iyisitolo sezidakamizwa esisethenjwayo nesincintisanayo ku-inthanethi. Sinesitoko esikhulu se-SGT-151, 5F-MDMB-2201, 4F-ADB kanye nama-cannabinoids okwenziwa. Uqinisekisiwe ukuthola ikhwalithi engcono kakhulu nezidakamizwa ezimsulwa kakhulu kithi.

Impumelelo yethu enkulu ukwethemba kwamakhasimende ethu nokholo kithi esilugcinile eminyakeni edlule ngokuhlinzeka ngemithi yamakhemikhali ehlanzekile, ephephile, nevikelekile. Uma uneminye imibuzo futhi ufuna ukwazi okwengeziwe ngemikhiqizo namasevisi ethu ungaxhumana nathi nganoma yisiphi isikhathi.

Chofoza lapha ukwazi okwengeziwe ngale cannabinoids yokwenziwa entsha sha.

Imininingwane engeziwe

Ubuningi

1kg, 500g, 250g, 100g, 50g, 5g